Hydrazine hydrate (1:1) → HCID 21995356, 화합물

HRID 1977677노트

반응식

HRID 1977677 반응식
C1(=O)[N:5]([CH2:6][CH2:7][CH2:8][O:9][C:10]2[CH:15]=[CH:14][C:13]([C:16]3[CH:21]=[CH:20][N:19]=[C:18]([NH:22][C:23]4[CH:28]=[C:27]([O:29][CH3:30])[C:26]([O:31][CH3:32])=[C:25]([O:33][CH3:34])[CH:24]=4)[N:17]=3)=[CH:12][CH:11]=2)C(=O)C2=CC=CC=C12.O.NN>>[NH2:5][CH2:6][CH2:7][CH2:8][O:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]2[CH:21]=[CH:20][N:19]=[C:18]([NH:22][C:23]3[CH:28]=[C:27]([O:29][CH3:30])[C:26]([O:31][CH3:32])=[C:25]([O:33][CH3:34])[CH:24]=3)[N:17]=2)=[CH:12][CH:11]=1

참가 물질

3

반응물 2

HCID 24654Hydrazine hydrate (1:1)HCID 21995252HCID 21995252, 화합물

생성물 1

HCID 21995356HCID 21995356, 화합물수율 10%

실험 절차

The compound was prepared in a manner analogous to the preparation of the compound of Example 48 from the compound of Example 50 (830 mg, 1.54 mmol) and hydrazine monohydrate (0.23 ml, 4.62 mmol) to give the title compound (63 mg) as a white solid m.p. 161-162°. MS m/z 411(M+H)+.

출처 및 근거

ORD 기록
ord-9d3a7753dace4894afc33a0ae60c95d8
출처 데이터셋
uspto-grants-2001_05
특허 번호
US06235746B1

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