Hydrochloric Acid → HCID 21994150, 화합물

HRID 1978498노트

반응식

HRID 1978498 반응식
[C:1]1([CH2:7][CH2:8][CH2:9][N:10]2[CH2:15][CH2:14][CH:13]([CH2:16][CH2:17][C:18](=[O:33])/[CH:19]=[CH:20]/[C:21]3[S:31][C:30]4[N:32]5[C:23](=[CH:24][N:25]=[C:26]5[CH:27]=[CH:28][CH:29]=4)[CH:22]=3)[CH2:12][CH2:11]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[ClH:34]>CO>[ClH:34].[ClH:34].[C:1]1([CH2:7][CH2:8][CH2:9][N:10]2[CH2:11][CH2:12][CH:13]([CH2:16][CH2:17][C:18](=[O:33])/[CH:19]=[CH:20]/[C:21]3[S:31][C:30]4[N:32]5[C:23](=[CH:24][N:25]=[C:26]5[CH:27]=[CH:28][CH:29]=4)[CH:22]=3)[CH2:14][CH2:15]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 21993866HCID 21993866, 화합물

생성물 1

HCID 21994150HCID 21994150, 화합물

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

In 2 ml of methanol was dissolved 0.281 g (E)-5-[1-(3-phenylpropan-1-yl)piperidin-4-yl]-1-(5-thia-1,8b-diazaacenaphthylen-4-yl)-1-penten-3-one, followed by addition of a stoichiometric excess of methanolic hydrochloric acid, and the mixture was stirred for 10 minutes. This reaction mixture was concentrated and crystallized from ethanol-diethyl ether to provide the title compound.

후처리

  1. concentrationThis reaction mixture was concentrated
  2. customcrystallized from ethanol-diethyl ether

출처 및 근거

ORD 기록
ord-689bffd7d4a9465684ba19e98cb11c87
출처 데이터셋
uspto-grants-2001_05
특허 번호
US06235731B1

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