Hydrochloric Acid → HCID 21993711, 화합물

HRID 1978500노트

반응식

HRID 1978500 반응식
C(OC([N:8]1[CH2:13][CH2:12][CH:11]([CH2:14][S:15](/[CH:18]=[CH:19]/[C:20]2[S:30][C:29]3[N:31]4[C:22](=[CH:23][N:24]=[C:25]4[CH:26]=[CH:27][CH:28]=3)[CH:21]=2)(=[O:17])=[O:16])[CH2:10][CH2:9]1)=O)(C)(C)C.[ClH:32]>C(O)C>[ClH:32].[ClH:32].[NH:8]1[CH2:13][CH2:12][CH:11]([CH2:14][S:15](/[CH:18]=[CH:19]/[C:20]2[S:30][C:29]3[N:31]4[C:22](=[CH:23][N:24]=[C:25]4[CH:26]=[CH:27][CH:28]=3)[CH:21]=2)(=[O:17])=[O:16])[CH2:10][CH2:9]1

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 86756772HCID 86756772, 화합물

생성물 1

HCID 21993711HCID 21993711, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

To the above crude (E)-4-[2-[1-(tert-butoxycarbon-yl)piperidin-4-ylmethanesulfonyl]vinyl]-5-thia-1,8b-diazaacenaphthylene was added 3 ml of concentrated hydrochloric acid, and the mixture was stirred at room temperature for 10 minutes. To this reaction mixture was added ethanol, and the resulting precipitate was recovered by filtration and rinsed serially with ethanol and diethyl ether to provide the title compound.

후처리

  1. filtrationthe resulting precipitate was recovered by filtration
  2. washrinsed serially with ethanol and diethyl ether

출처 및 근거

ORD 기록
ord-9c1b6533d2bb474ebdcd268d739f565c
출처 데이터셋
uspto-grants-2001_05
특허 번호
US06235731B1

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