HCID 21993984, 화합물 → 5-Thia-1,8b-diazaacenaphthylene-4-carbaldehyde

HRID 1978503노트

반응식

HRID 1978503 반응식
[N:1]1[CH:2]=[C:3]2[N:12]3[C:7](=[CH:8][CH:9]=[CH:10][C:11]=13)[S:6][C:5]([CH2:13][OH:14])=[CH:4]2>C(Cl)(Cl)Cl.[O-2].[O-2].[Mn+4]>[N:1]1[CH:2]=[C:3]2[N:12]3[C:7](=[CH:8][CH:9]=[CH:10][C:11]=13)[S:6][C:5]([CH:13]=[O:14])=[CH:4]2

참가 물질

4

반응물 1

HCID 21993984HCID 21993984, 화합물

생성물 1

HCID 219941445-Thia-1,8b-diazaacenaphthylene-4-carbaldehyde

시약·촉매·용매 2

HCID 178418406HCID 178418406, 화합물촉매HCID 6212Chloroform용매

실험 절차

To a solution of 1.073 g (5.253 mM) of 5-thia-1,8b-diazaacenaphthylene-4-methanol in 30 ml of chloroform was added 3 g of activated manganese dioxide (Aldrich) and the mixture was stirred at room temperature for 4 hours. This reaction mixture was filtered and the filter cake was washed with chloroform. The filtrate and washes were pooled and the solvent was distilled off under reduced pressure. The crude 5-thia-1,8b-diazaacenaphthylene-4-carbaldehyde thus obtained was not purified but used as it was in the next reaction.

후처리

  1. filtrationThis reaction mixture was filtered
  2. washthe filter cake was washed with chloroform
  3. distillationthe solvent was distilled off under reduced pressure

출처 및 근거

ORD 기록
ord-e8259484c79a4632a98412e63dc8f543
출처 데이터셋
uspto-grants-2001_05
특허 번호
US06235731B1

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