4-Chlorophenol → 1-(4-Chlorophenoxy)acetone

HRID 1978805노트

반응식

HRID 1978805 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1.Cl[CH2:10][C:11](=[O:13])[CH3:12].C(=O)([O-])[O-].[K+].[K+].[I-].[K+]>CC(C)=O>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][CH2:10][C:11](=[O:13])[CH3:12])=[CH:4][CH:3]=1

참가 물질

6

반응물 4

HCID 46844-ChlorophenolHCID 4875Potassium IodideHCID 6571ChloroacetoneHCID 11430Potassium Carbonate

생성물 1

HCID 2398741-(4-Chlorophenoxy)acetone수율 97.5%

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

4-Chlorophenol (10 g), chloroacetone (10.8 g), anhydrous potassium carbonate (12.9 g) and potassium iodide (1.3 g) were added to acetone (100 ml) and heated under reflux for 6 hours. The reaction mixture was filtered and the filtrate was concentrated to obtain 4-chlorophenoxyacetone (14 g).

후처리

  1. temperatureheated
  2. temperatureunder reflux for 6 hours
  3. filtrationThe reaction mixture was filtered
  4. concentrationthe filtrate was concentrated

출처 및 근거

ORD 기록
ord-cfa1616d65404d00b9f57ab28c931cd8
출처 데이터셋
uspto-grants-2001_05
특허 번호
US06239077B1

반응 노트

불러오는 중…