4-(3',4'-Dichloro-biphenyl-4-yl)-4-oxo-butyric acid, methyl ester → 4-(3',4'-Dichloro-4-biphenylyl)-4-oxo-butyric acid
반응식
[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:14]=[CH:13][C:12]([C:15](=[O:22])[CH2:16][CH2:17][C:18]([O:20]C)=[O:19])=[CH:11][CH:10]=2)[CH:5]=[CH:6][C:7]=1[Cl:8]>Cl>[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:10]=[CH:11][C:12]([C:15](=[O:22])[CH2:16][CH2:17][C:18]([OH:20])=[O:19])=[CH:13][CH:14]=2)[CH:5]=[CH:6][C:7]=1[Cl:8]참가 물질
3
실험 절차
In a manner similar to Example 4, Step (b), 4-(3′,4′-dichloro-biphenyl-4-yl)-4-oxo-butyric acid, methyl ester (1.360 g, 0.004033 mol) was refluxed in 6 M aqueous hydrochloric acid (25 mL) to give 1.280 g of 4-(3′,4′-dichloro-biphenyl-4-yl)-4-oxo-butyric acid as a white solid; mp 154-156° C.
출처 및 근거
- ORD 기록
- ord-c2a639c8107f460fa2ebded1f48cfbf7
- 출처 데이터셋
- uspto-grants-2001_05
- 특허 번호
- US06239288B1
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