Benzyl 1-aminocyclopentane-1-carboxylate → HCID 13376657, 화합물

HRID 1979753

반응식

HRID 1979753 반응식
[NH2:1][C:2]1([C:7]([O:9][CH2:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[O:8])[CH2:6][CH2:5][CH2:4][CH2:3]1.[CH3:17][O:18][C:19]([CH2:21][CH:22]([CH3:26])[C:23](O)=[O:24])=[O:20]>>[CH3:17][O:18][C:19]([CH2:21][CH:22]([CH3:26])[C:23]([NH:1][C:2]1([C:7]([O:9][CH2:10][C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=2)=[O:8])[CH2:6][CH2:5][CH2:4][CH2:3]1)=[O:24])=[O:20]

참가 물질

3

반응물 2

HCID 231228Benzyl 1-aminocyclopentane-1-carboxylateHCID 45639014-Methoxy-2-methyl-4-oxobutanoic acid

생성물 1

HCID 13376657HCID 13376657, 화합물

실험 절차

1-[(3-Methoxycarbonyl-2-methylpropanoyl)amino]-1-cyclopentanecarboxylic acid, benzyl ester was prepared as described in Example 3 from 10.96 g (0.050 mol) of 1-amino-1-cyclopentanecarboxylic acid, benzyl ester and 7.31 g (0.050 mol) of 3-methoxycarbonyl-2-methylpropionic acid. Crude di-ester crystallized to give 13.57 g (78%) of an off-white solid, mp: 88°-93°. This was used without further purification.

후처리

  1. customCrude di-ester crystallized

출처 및 근거

ORD 기록
ord-6e38844d57004eafbada95de2f3d7f27
출처 데이터셋
uspto-grants-1984_11
특허 번호
US04482572

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