HCID 13502856, 화합물 → HCID 13502857, 화합물

HRID 1980323노트

반응식

HRID 1980323 반응식
[Cl:1][C:2]1[N:7]=[C:6]([NH:8]C=O)[C:5]([C:11]([O:13][CH2:14][CH3:15])=[O:12])=[CH:4][C:3]=1[C:16]1[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][CH:17]=1>C(O)C.Cl>[NH2:8][C:6]1[C:5]([C:11]([O:13][CH2:14][CH3:15])=[O:12])=[CH:4][C:3]([C:16]2[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][CH:17]=2)=[C:2]([Cl:1])[N:7]=1

참가 물질

4

반응물 1

HCID 13502856HCID 13502856, 화합물

생성물 1

HCID 13502857HCID 13502857, 화합물

시약·촉매·용매 2

HCID 313Hydrochloric Acid촉매HCID 702Ethanol용매

실험 절차

6-Chloro-5-(4-chlorophenyl)-2-formamido-3-pyridinecarboxylic acid, ethyl ester (0.5 gram) was partially dissolved in 50 ml ethanol and treated with about 5-6 drops concentrated HCl. The reaction mixture was refluxed for approximately 3 hours, and upon cooling, a solid precipitate was collected, yield 350 mg, m.p. 195°-198° C.

후처리

  1. temperatureThe reaction mixture was refluxed for approximately 3 hours
  2. temperatureupon cooling
  3. customa solid precipitate was collected

출처 및 근거

ORD 기록
ord-4fbd020b503f4be483ad8ff7103c3416
출처 데이터셋
uspto-grants-1985_04
특허 번호
US04508722

반응 노트

불러오는 중…