Potassium Carbonate → [[7-(2-Propenyloxy)-2-naphthalenyl]oxy]acetic acid methyl ester

HRID 1981997노트

반응식

HRID 1981997 반응식
[CH2:1]([O:4][C:5]1[CH:14]=[C:13]2[C:8]([CH:9]=[CH:10][C:11]([OH:15])=[CH:12]2)=[CH:7][CH:6]=1)[CH:2]=[CH2:3].C(=O)([O-])[O-].[K+].[K+].Br[CH2:23][C:24]([O:26][CH3:27])=[O:25]>CC(C)=O>[CH3:27][O:26][C:24](=[O:25])[CH2:23][O:15][C:11]1[CH:10]=[CH:9][C:8]2[C:13](=[CH:14][C:5]([O:4][CH2:1][CH:2]=[CH2:3])=[CH:6][CH:7]=2)[CH:12]=1

참가 물질

5

반응물 3

HCID 11430Potassium CarbonateHCID 60984Methyl bromoacetateHCID 111716387-(2-Propenyloxy)-2-naphthalenol

생성물 1

HCID 13504790[[7-(2-Propenyloxy)-2-naphthalenyl]oxy]acetic acid methyl ester

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

A mixture of 7.9 g of 7-(2-propenyloxy)-2-naphthalenol and 8.3 g of potassium carbonate in 50 ml of anhydrous acetone was stirred at room temperature for 1.5 hours. Methyl bromoacetate (4.7 ml), was added and stirring was continued for 18 hours. The reaction mixture was filtered and the filtrate was concentrated in vacuo to yield (8.4 g) of [[7-(2-propenyloxy)-2-naphthalenyl]oxy]acetic acid methyl ester, mp 69°-70° after recrystallization from ether-hexane.

후처리

  1. stirringstirring
  2. waitwas continued for 18 hours
  3. filtrationThe reaction mixture was filtered
  4. concentrationthe filtrate was concentrated in vacuo

출처 및 근거

ORD 기록
ord-3a7ebf52387947be97c4a3eedf517466
출처 데이터셋
uspto-grants-1986_06
특허 번호
US04594442

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