Butylamine → N-Butylmethacrylamide
반응식
[CH2:1]([NH2:5])[CH2:2][CH2:3][CH3:4].[C:6](Cl)(=[O:10])[C:7]([CH3:9])=[CH2:8]>C1COCC1>[CH2:1]([NH:5][C:6](=[O:10])[C:7]([CH3:9])=[CH2:8])[CH2:2][CH2:3][CH3:4]참가 물질
4
반응 조건
- 온도
- 5 °C
실험 절차
In a 1 liter 3-necked flask were combined 400 ml dry THF and 40 ml distilled n-butylamine (0.405 mol). After cooling to 5° C. in an ice bath, 20 ml (0.205 mol) methacryloyl chloride was added slowly so as to keep the temperature below 10° C. The precipitate was removed by filtration, and the filtrate concentrated on a rotary evaporator. 1 g DNPD was added and the oil distilled at 76°-78° C. and 20 m torr. Yield 24.3 g (84%).
후처리
- customIn a 1 liter 3-necked flask were combined
- customthe temperature below 10° C
- customThe precipitate was removed by filtration
- concentrationthe filtrate concentrated on a rotary evaporator
- addition1 g DNPD was added
- distillationthe oil distilled at 76°-78° C.
출처 및 근거
- ORD 기록
- ord-ed2f99d572ba441ea7927338c4b4af02
- 출처 데이터셋
- uspto-grants-1986_06
- 특허 번호
- US04596858
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