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메타크릴산 클로라이드

Methacryloyl chloride

HCID 13528
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기본 정보개요이름 및 식별자물성안전 및 규제화학 및 산업관련 반응화합물 노트
부분 구조 검색유사 구조 찾기

기본 정보

CAS
920-46-7
표준 SMILES
C=C(C)C(=O)Cl
InChIKey
VHRYZQNGTZXDNX-UHFFFAOYSA-N
분자식
C4H5ClO
평균 분자량
104.53 g/mol
단동위원소 질량
104.00289246

개요

Methacryloyl chloride appears as a liquid of density 1.07 g / cm3, boiling point 95-96 °C, and flash point 55 °F. Highly toxic. Supplied in technical grades of varying purity.

이름 및 식별자

우선 이름
Methacryloyl chloride
IUPAC
2-methylprop-2-enoyl chloride
현지명
메타크릴산 클로라이드
영어명
Methacryloyl chloride
분자식
C4H5ClO
분자량
104.53

이름 및 동의어

METHACRYLOYL CHLORIDE920-46-7Methacrylyl chloride2-Methyl-2-propenoyl chlorideMethacrylic acid chlorideMethacryl chloride2-Propenoyl chloride, 2-methyl-Methacrylic chloride2-Methylpropenoyl chlorideMethylacryloyl chloride2-Methylpropenoic acid chlorideL76O6653IO
이름 더 보기
메타크릴로일클로라이드메타크릴로일염화물메타크릴산클로라이드염화2-메틸-2-프로페노일메타크릴로일 클로라이드염화 2-메틸-2-프로페노일Methacryloyl chlorid2-METHYL-ACRYLOYL CHLORIDEmethylacryloylchloridemethacrylchloridemethacrylolchloridemethacrylicchloride
alpha-Methylacryloyl chlorideDTXSID6061280RefChem:811289DTXCID8048785213-058-9Methacryloylchloride2-methylprop-2-enoyl chloride.alpha.-Methylacryloyl chloride

데이터베이스 식별자

CAS
920-46-7
PubChem CID
13528
DTXSID
DTXSID6061280
UNII
L76O6653IO
EC Number
213-058-9
Nikkaji
J38.880G

물성

구조 계산 물성보충 중

XLogP
1.7
극성 표면적
17.1 Ų
수소 결합 공여자 수
0
수소 결합 수용자 수
1
회전 가능 결합 수
1
무거운 원자 수
6
형식 전하
0
복잡도
85.5

실험 및 물리화학적 성질

Chemical Classes · 2건

Toxic Gases & Vapors -> Other Toxic Gases & Vapors

Corrosives

SpringerMaterials PropertiesSchoenflies notation
Density · 2건

1.0871 at 68 °F (EPA, 1998) - Denser than water; will sink

1.0871 g/cu cm @ 20 °C

SolubilitySol in ether, acetone, chloroform
Boiling Point · 3건

205 °F at 760 mmHg (EPA, 1998)

96 °C

96 °C @760 [mm Hg]

DecompositionWhen heated to decomposition it emits toxic fumes of /hydrogen chloride/.
Melting Point · 2건

-60 °C

-60 °C

Vapor Pressure · 2건

45.5 [mmHg]

40 [mm Hg] @25 °C

Refractive IndexIndex of refraction: 1.4435 at 20 °C/D
Physical Description · 2건

안전 및 규제

안전 정보는 참고용이며, 공급업체의 물질안전보건자료(SDS), 관련 법규 및 전문가 평가를 대체하지 않습니다.

GHS 분류

GHS Classification · 6건

Danger

H225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]

P210, P233, P240, P241, P242, P243, P260, P261, P264, P270, P271, P272, P273, P280, P284, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P320, P321, P330, P333+P317, P362+P364, P363, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 53 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

H225: Highly Flammable liquid and vapor [Danger Flammable liquids]

유해성 정보

Regulatory Information · 2건

Status: Active Update: 12-03-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/23665

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

DOT LabelFlammable Liquid Poison Corrosive
Fire HazardsExcerpt from ERG Guide 131 [Flammable Liquids - Toxic]:
Health HazardsExcerpt from ERG Guide 131 [Flammable Liquids - Toxic]:
Hazards Summary · 1건

Flammable and corrosive; [Hawley] A strong skin irritant; [HSDB] Reacts with water evolving hydrogen chloride gas; Highly flammable and toxic; [CAMEO] A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis; [MSDSonline]

Reactive GroupAcyl Halides, Sulfonyl Halides, and Chloroformates

화학 및 산업

용도 및 제조

Uses · 2건

Used in the production of hydrogel for contact lenses; [HSDB]

A hydrogel with 80% water absorption was obtained from reaction of 2-hydroxyethyl methacrylate, containing small amounts of ethylene glycol dimethacrylate with the reaction product of poly(vinylpyrrolidinone) & methacryloyl chloride /contact lenses/

Formulations/PreparationsAvailable forms: Technical 90% stabilized with phenothiazine
General Manufacturing Information2-Propenoyl chloride, 2-methyl-: ACTIVE
응용 분야 · 2건

용도메타크릴산 클로라이드 는 고분자 제조에 사용될 수 있는 고효율 기능성 단량체입니다. 이 물질은 자체 중합에 사용되거나, 새로운 고성능 박막 소재를 제조하기 위한 화학 개질 시약으로 활용될 수 있습니다. 또한 특정 아로마틱 메틸아크릴레이트 광감응성 소재의 핵심 원료로도 사용됩니다. 이러한 생성물은 광경화성 수지의 활성 성분으로서, 고급 코팅, 포토레지스트 및 의료용 소재 분야에 활용될 수 있습니다.

일반 설명Methacryloyl chloride is the clear to slightly colored acid chloride of methacrylic acid. It appears as a liquid of density 1.07g/cm3, boiling point 95-96°C, and flash point 55°F. Highly toxic. Supplied in technical grades of varying purity. Monomethyl ether hydroquinone is added as a stabilizer to prevent auto polymerization. Reaction with diisopropyl ether in presence of metal salts is rigorous.

상·하류 제품 정보

하류 제품

비나파크릴클로라노크릴optical plastics based on coplymer of diene macromolecule메타크릴산 벤질4-Benzoylphenyl Methacrylate

관련 반응

674건
반응 기록 만들기
HRID 2679 반응식
HRID 2679반응물로uspto-grants-1998_03
HRID 3078 반응식
HRID 3078반응물로uspto-grants-1998_03
HRID 5050 반응식
HRID 5050반응물로uspto-grants-1993_09
HRID 41846 반응식
HRID 41846반응물로uspto-grants-2013_09
HRID 41848 반응식
HRID 41848반응물로uspto-grants-2013_09
HRID 44126 반응식
HRID 44126반응물로uspto-grants-2013_09
HRID 45411 반응식
HRID 45411반응물로uspto-grants-2013_09
HRID 45706 반응식
HRID 45706반응물로uspto-grants-2013_09
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Methacryloyl chloride appears as a liquid of density 1.07 g / cm3, boiling point 95-96 °C, and flash point 55 °F. Highly toxic. Supplied in technical grades of varying purity.

Liquid; [Hawley] Colorless liquid; [MSDSonline]

Other Experimental PropertiesHydrolyzed by water

물리화학적 성질

녹는점
-60 °C · -60°C
끓는 점
95 to · 95 to 96 °C (203 to 205 °F; 368 to 369 K)
밀도
1.07 g/mL · 1.07 g/mL
굴절률
1.45 · 1.45
인화점
12.8 °C · 12.8 °C
저장 조건
2 · 2-8°C
용해도
클로로포름에 용해됨
물리적 상태
clear liquid
색상
Colorless to Red to Green
수용성
알코올, 에테르, 유기용매와 섞일 수 있습니다. 물과 약간 섞임.
BRN
878175 · 878175
안정성
빛과 습기에 민감함
InChIKey
VHRYZQNGTZXDNX-UHFFFAOYSA-N
NIST
Methacryloyl chloride(920-46-7)
EPA
Methacryloyl chloride (920-46-7)

화학적 성질

clear slightly colored liquid

Reactivity Alerts
Highly Flammable
Reactivity Profile · 1건

METHACRYLOYL CHLORIDE is incompatible with strong oxidizing agents, alcohols, bases (including amines). Can polymerize violently; but the polymerization reaction can be inhibited by the addition of phenolthiazine. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].

Air and Water ReactionsHighly flammable. Reacts with water to produce gaseous hydrogen chloride (corrosive and toxic).
Highly Hazardous SubstanceChemical: Methacryloyl Chloride
CERCLA Reportable Quantities · 1건

Releases of CERCLA hazardous substances are subject to the release reporting requirement of CERCLA section 103, codified at 40 CFR part 302, in addition to the requirements of 40 CFR part 355. Methacryloyl chloride is an extremely hazardous substance (EHS) subject to reporting requirements when stored in amounts in excess of its threshold planning quantity (TPQ) of 100 lbs.

Hazard Classes and Categories · 3건

Flam. Liq. 2 (100%)

Flammable liquids - Category 2

Corrosives, Flammable agents - 3rd degree, Reactive agents - 1st degree

안전 및 보호

Fire FightingExcerpt from ERG Guide 131 [Flammable Liquids - Toxic]:
First AidNote: No information on specific clinical effects of acute exposure to methacryloyl chloride was found.
Nonfire Spill ResponseExcerpt from ERG Guide 131 [Flammable Liquids - Toxic]:
Disposal Methods · 1건

SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.

Isolation and EvacuationExcerpt from ERG Guide 131 [Flammable Liquids - Toxic]:
Protective Action Criteria (PAC) · 3건

0.055 [mg/m3]

0.60 [mg/m3]

2.6 [mg/m3]

Personal Protective Equipment (PPE) · 1건

For emergency situations, wear a positive pressure, pressure-demand, full facepiece self-contained breathing apparatus (SCBA) or pressure- demand supplied air respirator with escape SCBA and a fully-encapsulating, chemical resistant suit. (EPA, 1998)

독성 정보

Adverse EffectsDermatotoxin - Skin burns.
Human Toxicity ExcerptsConcn of up to 113 ppm were found in a plant handling the material. Medical reports of acute exposures revealed no resp symptoms, but skin toxicity and a severe corneal burn. /Methacrylic acid/
Non-Human Toxicity Excerpts · 2건

... severe corneal burns have been reported after acute exposure to methacrylic acid. /Methacrylic acid/

Direct contact with liquid methacrylic acid can result in blindness ... /Methacrylic acid/

Antidote and Emergency Treatment · 2건

Basic treatment: Establish a patent airway. Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if needed. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with normal saline during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 mL/kg up to 200 mL of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Cover skin burns with dry sterile dressings after decontamination ... . /Poisons A and B/

Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious, has severe pulmonary edema, or is in respiratory arrest. Positive-pressure ventilation techniques with a bag-valve-mask device may be beneficial. Monitor cardiac rhythm and treat arrhythmias as necessary ... . Start an IV with D5W TKO /SRP: "To keep open", minimal flow rate/. Use lactated Ringer's if signs of hypovolemia are present. Watch for signs of fluid overload. Consider drug therapy for pulmonary edema ... . For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam (Valium) ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Poisons A and B/

Toxicity DataLC50 (rat) = 60 mg/m3/4h
Non-Human Toxicity Values · 2건

LC50 Rat ihl 60 mg/cu m/4 hr

LC50 Mouse ihl 115 mg/cu m/2 hr

규제 정보

CERCLA Reportable Quantities · 1건

Releases of CERCLA hazardous substances are subject to the release reporting requirement of CERCLA section 103, codified at 40 CFR part 302, in addition to the requirements of 40 CFR part 355. Methacryloyl chloride is an extremely hazardous substance (EHS) subject to reporting requirements when stored in amounts in excess of its threshold planning quantity (TPQ) of 100 lbs.

안전 데이터

wgk
3
tsca
TSCA listed
rtecs
OZ5791000
ridadr
UN 3383 6.1/PG 1
HS 번호
2916190090
risk_code
11-26/27/28-34-26-22-43-52/53
hazard_code
F,T+,Xi
safety_code
26-28-36/37/39-45-27-16-33-29
포장분류
I
위험 등급
6.1
기존화학 물질
KE-05-0853
F 고인화성물질
21
위험 참고 사항
Irritant
유해 물질 데이터
920-46-7(Hazardous Substances Data)
함량 및 규제정보
물질구분: 유독물질; 혼합물(제품)함량정보: 염화2-메틸-2-프로페노일 및 이를 1% 이상 함유한 혼합물
유해화학물질 필터링
2001-1-522
메틸트리글리콜메타크릴레이트
2-메틸-N-(4-설파모일-페닐)-아크릴아미드
데실메타크릴레이트
메타크릴산이소프로필에스테르
TEMPO메타크릴레이트
N-숙신이미딜메타크릴레이트
2-에틸-2-아다멘틸 메타아크릴레이트
메타아크릴산 3-클로로-2-히드록시프로필
메타크릴산-2-에톡시에틸에스테르
12-히드록시도데실메타크릴레이트