Trimethyl borate → 4-(Difluoromethoxy)benzeneboronic acid

HRID 19830

반응식

HRID 19830 반응식
[F:1][CH:2]([F:11])[O:3][C:4]1[CH:9]=[CH:8][C:7](I)=[CH:6][CH:5]=1.C([Mg]Cl)(C)C.[B:17](OC)([O:20]C)[O:18]C>>[F:1][CH:2]([F:11])[O:3][C:4]1[CH:9]=[CH:8][C:7]([B:17]([OH:20])[OH:18])=[CH:6][CH:5]=1

참가 물질

4

실험 절차

In a departure from the procedure described above the compound is prepared from 4-difluoromethoxy-1-iodo-benzene using iPrMgCl to generate the arylmetal compound and trapping this intermediate with trimethyl borate.

출처 및 근거

ORD 기록
ord-1be23ea1523a4716b40cd994300a4a50
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07745414B2

연결된 노트

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