Thionyl Chloride → HCID 23149146, 화합물

HRID 1983056노트

반응식

HRID 1983056 반응식
[Cl:1][C:2]([Cl:12])([F:11])[S:3][C:4]1[CH:5]=[N:6][N:7]([CH2:9]O)[CH:8]=1.S(Cl)([Cl:15])=O>C(Cl)(Cl)Cl>[Cl:15][CH2:9][N:7]1[CH:8]=[C:4]([S:3][C:2]([Cl:12])([Cl:1])[F:11])[CH:5]=[N:6]1

참가 물질

4

반응물 2

HCID 24386Thionyl ChlorideHCID 23149182HCID 23149182, 화합물

생성물 1

HCID 23149146HCID 23149146, 화합물

시약·촉매·용매 1

HCID 6212Chloroform용매

실험 절차

0.22 g of 4-{[dichlorofluoromethyl]thio}-1H-pyrazole-1-ylmethanol was dissolved to 10 ml of chloroform. 0.3 ml of thionyl chloride was added to the solution, and refluxed for 4 hours. The reaction mixture was concentrated under reduced pressure to obtain 0.21 g of 1-(chloromethyl)-4-{[dichloro(fluoro)methyl]thio}-1H-pyrazole.

후처리

  1. temperaturerefluxed for 4 hours
  2. concentrationThe reaction mixture was concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-6b2fd82e842a4c069fd14c3887b6affe
출처 데이터셋
uspto-grants-2009_06
특허 번호
US07541374B2

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