Cyclopropylamine → 2-{5-Chloro-2-[3-(4-methylpiperazin-1-yl)-propylamino]-pyrimidin-4-yl}-benzo[b]thiophene-6-carboxylic acid cyclopropylamide tri-hydrochloride

반응식

C(N(C(C)C)CC)(C)C.[CH:10]1([NH2:13])[CH2:12][CH2:11]1.F[P-](F)(F)(F)(F)F.N1(O[P+](N(C)C)(N(C)C)N(C)C)C2C=CC=CC=2N=N1.[ClH:41].Cl.Cl.[Cl:44][C:45]1[C:46]([C:62]2[S:66][C:65]3[CH:67]=[C:68]([C:71](O)=[O:72])[CH:69]=[CH:70][C:64]=3[CH:63]=2)=[N:47][C:48]([NH:51][CH2:52][CH2:53][CH2:54][N:55]2[CH2:60][CH2:59][N:58]([CH3:61])[CH2:57][CH2:56]2)=[N:49][CH:50]=1.[Li+].[Cl-]>CN(C=O)C>[ClH:44].[ClH:41].[ClH:44].[CH:10]1([NH:13][C:71]([C:68]2[CH:69]=[CH:70][C:64]3[CH:63]=[C:62]([C:46]4[C:45]([Cl:44])=[CH:50][N:49]=[C:48]([NH:51][CH2:52][CH2:53][CH2:54][N:55]5[CH2:60][CH2:59][N:58]([CH3:61])[CH2:57][CH2:56]5)[N:47]=4)[S:66][C:65]=3[CH:67]=2)=[O:72])[CH2:12][CH2:11]1