Methanol → N-[4-(8-azabicyclo[3.2.1]oct-8-yl)-3-(trifluoromethyl)benzyl]-N'-1H-indazol-4-ylurea

HRID 198669노트

반응식

[CH3:39][OH:40].[CH:1]12[CH2:2][CH2:3][CH2:4][CH:5]([CH2:6][CH2:7]1)[N:8]2[c:9]1[c:10]([C:33]([F:34])([F:35])[F:36])[cH:11][c:12]([CH2:13][NH:14][C:15](=[O:16])[NH:17][c:18]2[c:19]3[cH:20][n:21][n:22]([C:27]([O:28][CH3:29])=[O:30])[c:23]3[cH:24][cH:25][cH:26]2)[cH:31][cH:32]1.[Na+:38].[OH-:37]>>[CH:1]12[CH2:2][CH2:3][CH2:4][CH:5]([CH2:6][CH2:7]1)[N:8]2[c:9]1[c:10]([C:33]([F:34])([F:35])[F:36])[cH:11][c:12]([CH2:13][NH:14][C:15](=[O:16])[NH:17][c:18]2[c:19]3[cH:20][n:21][nH:22][c:23]3[cH:24][cH:25][cH:26]2)[cH:31][cH:32]1