Chloroacetone → HCID 57725267, 화합물

HRID 1987833노트

반응식

[CH2:1]([O:8][C:9]1[C:10]([CH2:15][C:16]([O:18][CH3:19])=[O:17])=[N:11][CH:12]=[CH:13][CH:14]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[CH2:21][C:22](=O)[CH3:23]>>[CH2:1]([O:8][C:9]1[C:10]2[N:11]([CH:21]=[C:22]([CH3:23])[C:15]=2[C:16]([O:18][CH3:19])=[O:17])[CH:12]=[CH:13][CH:14]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

반응물 2

HCID 6571Chloroacetone

HCID 57725265HCID 57725265, 화합물

생성물 1

HCID 57725267HCID 57725267, 화합물

실험 절차

This compound is obtained according to the same procedure as the compound of Preparation III using the Tschitschibabin reaction, starting with 25.82 g of methyl 2-[3-(benzyloxy)pyridin-2-yl]acetate [according to J. Med. Chem.; (1996), 39(19), 3636-3658] and chloroacetone.

후처리

customThis compound is obtained
customthe Tschitschibabin reaction

출처 및 근거

ORD 기록: ord-ae653473eb4444228f254d8d88fd856b
출처 데이터셋: uspto-grants-2009_06
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07553845B2

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