Propylamine → N-Cyclopropyl-4-methyl-3-{1-[2-oxo-2-(propylamino)ethyl]-1H-indazol-5-yl}benzamide
반응식
[CH:1]1([NH:4][C:5]([C:7]2[CH:8]=[CH:9][C:10]([CH3:27])=[C:11]([C:13]3[CH:14]=[C:15]4[C:19](=[CH:20][CH:21]=3)[N:18]([CH2:22][C:23](OC)=[O:24])[N:17]=[CH:16]4)[CH:12]=2)=[O:6])[CH2:3][CH2:2]1.[CH2:28]([NH2:31])[CH2:29][CH3:30]>>[CH:1]1([NH:4][C:5](=[O:6])[C:7]2[CH:8]=[CH:9][C:10]([CH3:27])=[C:11]([C:13]3[CH:14]=[C:15]4[C:19](=[CH:20][CH:21]=3)[N:18]([CH2:22][C:23](=[O:24])[NH:31][CH2:28][CH2:29][CH3:30])[N:17]=[CH:16]4)[CH:12]=2)[CH2:2][CH2:3]1참가 물질
3
실험 절차
Example 128 was prepared by General Method D using methyl (5-{5-[(cyclopropylamino)carbonyl]-2-methylphenyl}-1H-indazol-1-yl)acetate (Example 117) and 1-propylamine to give the title compound (0.011 g).
후처리
- customExample 128 was prepared by General Method D
출처 및 근거
- ORD 기록
- ord-7e06d919d167402f9f74fd2fce3d8234
- 출처 데이터셋
- uspto-grants-2010_01