Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-(Benzenesulfonyl)piperazine → (4-Benzenesulfonyl-piperazin-1-yl)-[5-(4-isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-methanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-(Benzenesulfonyl)piperazine | HCID 808712 | — |
| 반응물 | [5-(4-Isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-(4-methanesulfonyl-piperazin-1-yl)-methanone | HCID 68538245 | — |
| 생성물 | (4-Benzenesulfonyl-piperazin-1-yl)-[5-(4-isopropyl-piperazine-1-carbonyl)-1H-indol-2-yl]-methanone | HCID 68535846 | 92% |
반응 단계
The title compound was synthesized in analogy to example 1, from 5-(4-isopropyl-piperazine-1-carbonyl)-1H-indole-2-carboxylic acid hydrochloride (example 1, intermediate b) and 1-benzenesulfonyl-piperazine to afford the desired product as a light-brown foam (92%). MS (ISP): 524.2 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07648979B2 |
| 출처 데이터셋 | uspto-grants-2010_01 |
| ORD ID | ord-8f7edb21f40146ef83d62e0a66e79c67 |
| 출처 메모 | uspto-grants-2010_01 |