Benzoic acid, 2-chloro-6-nitro-, methyl ester → Methyl 2-amino-6-chlorobenzoate
반응식
[Cl:1][C:2]1[C:7]([C:8]([O:10][CH3:11])=[O:9])=[C:6]([N+:12]([O-])=O)[CH:5]=[CH:4][CH:3]=1.[H][H]>[Ni].CO>[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]([NH2:12])[C:7]=1[C:8]([O:10][CH3:11])=[O:9]참가 물질
5
실험 절차
4.5 gm (0.212 mol) of methyl 6-chloro-2-nitro-benzoate were hydrogenated with Raney nickel in 1.8 liters of methanol until the calculated amount of hydrogen was absorbed. The filtered reaction mixture was evaporated in vacuo, and the residue was distilled in vacuo.
후처리
- customwas absorbed
- customThe filtered reaction mixture
- customwas evaporated in vacuo
- distillationthe residue was distilled in vacuo
출처 및 근거
- ORD 기록
- ord-ff8c8899ad384fc487339258c97eb69f
- 출처 데이터셋
- uspto-grants-1983_09
- 특허 번호
- US04404230
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