2-Pyrrolidone → N-(hydroxyethoxyethoxyethyl)pyrrolidine
반응식
[NH:1]1[CH2:5][CH2:4][CH2:3][C:2]1=O.Cl[CH2:8][CH2:9][O:10][CH2:11][CH2:12][O:13][CH:14](O)[CH3:15].[OH-:17].[K+]>C(O)C>[OH:17][CH2:8][CH2:9][O:10][CH2:11][CH2:12][O:13][CH2:14][CH2:15][N:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1참가 물질
5
실험 절차
A total of 295 g of pyrrolidone and 250 g of 2-chloroethoxyethoxyethanol in 750 ml of ethanol was refluxed for 5 hours. The reaction mixture was then treated with 106 g of KOH and refluxed for an additional hour. Filtration and distillation yielded 229 g of N-(hydroxyethoxyethoxyethyl)pyrrolidine (b.p.=145° C. at 3 mm).
후처리
- temperaturerefluxed for an additional hour
- filtrationFiltration and distillation
출처 및 근거
- ORD 기록
- ord-022f33e858d94b358a17e7546382fa75
- 출처 데이터셋
- uspto-grants-1983_09
- 특허 번호
- US04405582
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