Bromine → 1,4-Bis-(4-chlorophenoxy)-1-bromo-3,3-dimethyl-butan-2-one

HRID 1995919노트

반응식

HRID 1995919 반응식
[Cl:1][C:2]1[CH:23]=[CH:22][C:5]([O:6][CH2:7][C:8](=[O:21])[C:9]([CH3:20])([CH3:19])[CH2:10][O:11][C:12]2[CH:17]=[CH:16][C:15]([Cl:18])=[CH:14][CH:13]=2)=[CH:4][CH:3]=1.[Br:24]Br>C(Cl)(Cl)Cl>[Cl:1][C:2]1[CH:23]=[CH:22][C:5]([O:6][CH:7]([Br:24])[C:8](=[O:21])[C:9]([CH3:19])([CH3:20])[CH2:10][O:11][C:12]2[CH:17]=[CH:16][C:15]([Cl:18])=[CH:14][CH:13]=2)=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 24408BromineHCID 127659691,4-Bis-(4-chlorophenoxy)-3,3-dimethyl-butan-2-one

생성물 1

HCID 127659701,4-Bis-(4-chlorophenoxy)-1-bromo-3,3-dimethyl-butan-2-one수율 100%

시약·촉매·용매 1

HCID 6212Chloroform용매

실험 절차

36.6 g (0.1 mol) of 1,4-bis-(4-chlorophenoxy)-3,3-dimethyl-butan-2-one were dissolved in 250 ml of chloroform, and 16.6 g (0.1 mol) of bromine were added dropwise at 20° C. in a manner such that continuous decolorization occurred. After the addition, the mixture was subsequently stirred at room temperature for 30 minutes and was then concentrated by distilling off the solvent in vacuo. 43.2 g (quantitative conversion) of 1,4-bis-(4-chlorophenoxy)-1-bromo-3,3-dimethyl-butan-2-one were obtained as an oil, which was further reacted directly.

후처리

  1. additionAfter the addition
  2. concentrationwas then concentrated
  3. distillationby distilling off the solvent in vacuo

출처 및 근거

ORD 기록
ord-8a7b1064960540a090b3dbd800edf738
출처 데이터셋
uspto-grants-1983_09
특허 번호
US04406909

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