tert-Butyl 3-amino-3-methylpyrrolidine-1-carboxylate → Tert-butyl 3-(4-chloro-2-morpholin-4-yl-5,6-dihydropyrrolo[2,3-d]pyrimidin-7-yl)-3-methylpyrrolidine-1-carboxylate
반응식
[CH3:1][C:2]([O:5][C:6]([N:8]1[CH2:14][C:11]([NH2:13])([CH3:12])[CH2:10][CH2:9]1)=[O:7])([CH3:4])[CH3:3].CS(O[CH2:15][CH2:16][c:17]1[c:23](Cl)[n:22][c:21]([N:24]2[CH2:29][CH2:28][O:27][CH2:26][CH2:25]2)[n:20][c:18]1[Cl:19])(=O)=O>>[CH3:1][C:2]([O:5][C:6]([N:8]1[CH2:14][C:11]([N:13]2[c:23]([c:17]3[CH2:16][CH2:15]2)[n:22][c:21]([N:24]4[CH2:29][CH2:28][O:27][CH2:26][CH2:25]4)[n:20][c:18]3[Cl:19])([CH3:12])[CH2:10][CH2:9]1)=[O:7])([CH3:4])[CH3:3]참가 물질
6
반응물 2
생성물 1
시약·촉매·용매 3
반응 조건
- 온도
- 120 °C
출처 및 근거
- ORD 기록
- ord-e1908317e7a94359b59c024e30e78245
- 출처 데이터셋
- 39k HTE dataset from Pfizer
- 원본 링크
- 출처 보기
반응 노트
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