Ethyl 5-amino-1-phenyl-1H-pyrazole-3-carboxylate → ethyl 5-(2,4-dichloro-5-(pyridin-2-yl)benzamido)-1-phenyl-1H-pyrazole-3-carboxylate

HRID 2000389

반응식

HRID 2000389 반응식
O[C:1]([c:3]1[c:9]([Cl:10])[cH:8][c:6]([Cl:7])[c:5]([c:11]2[n:16][cH:15][cH:14][cH:13][cH:12]2)[cH:4]1)=[O:2].[CH3:17][CH2:18][O:19][C:20]([c:22]1[n:27][n:26]([c:28]2[cH:33][cH:32][cH:31][cH:30][cH:29]2)[c:24]([NH2:25])[cH:23]1)=[O:21]>>[CH3:17][CH2:18][O:19][C:20]([c:22]1[n:27][n:26]([c:28]2[cH:33][cH:32][cH:31][cH:30][cH:29]2)[c:24]([NH:25][C:1]([c:3]3[c:9]([Cl:10])[cH:8][c:6]([Cl:7])[c:5]([c:11]4[n:16][cH:15][cH:14][cH:13][cH:12]4)[cH:4]3)=[O:2])[cH:23]1)=[O:21]

참가 물질

7

반응물 2

HCID 23630921Ethyl 5-amino-1-phenyl-1H-pyrazole-3-carboxylateHCID 1184970902,4-Dichloro-5-(pyridin-2-yl)benzoic acid

생성물 1

HCID 118497071ethyl 5-(2,4-dichloro-5-(pyridin-2-yl)benzamido)-1-phenyl-1H-pyrazole-3-carboxylate

시약·촉매·용매 4

HCID 81531Diisopropylethylamine시약HCID 1716312-Fluoro-1-methylpyridinium p-toluenesulfonate시약HCID 6228Dimethylformamide용매HCID 117669-Phenylanthracene내부 표준

반응 조건

온도
25 °C

출처 및 근거

ORD 기록
ord-5f090c45590d475b863f042e82998d3c
출처 데이터셋
39k HTE dataset from Pfizer
원본 링크
출처 보기

연결된 노트

불러오는 중…