Hydrochloric Acid → Hydrochloric Acid

HRID 20094노트

반응식

HRID 20094 반응식
[N:1]([C:4]1[C:5]([NH:11]C(=O)C(C)(C)C)=[N:6][CH:7]=[C:8]([F:10])[CH:9]=1)=[N+:2]=[N-:3].[ClH:18]>>[N:1]([C:4]1[C:5]([NH2:11])=[N:6][CH:7]=[C:8]([F:10])[CH:9]=1)=[N+:2]=[N-:3].[ClH:18]

참가 물질

4

반응물 2

HCID 313Hydrochloric AcidHCID 22293288N-(3-Azido-5-fluoropyridin-2-yl)-2,2-dimethylpropanamide

생성물 2

HCID 313Hydrochloric AcidHCID 222932423-Azido-5-fluoropyridin-2-amine

실험 절차

N-(3-Azido-5-fluoropyridin-2-yl)-2,2-dimethylpropanamide (275 mg, 1.16 mmol) in 3 N HCl (5 mL) was heated to 100° C. After 2 h, the volatiles were removed in vacuo, to give the title compound as its HCl salt (180 mg). MS154.2 (M+1).

후처리

  1. customthe volatiles were removed in vacuo

출처 및 근거

ORD 기록
ord-85f631a64d1f456f809694e9f8f1ed62
출처 데이터셋
uspto-grants-2010_06
특허 번호
US07745427B2

반응 노트

불러오는 중…