Trimethylsilylacetylene → 2-tert-Butyl-6-trimethylsilanylethynyl-[1,2,4]triazolo[1,5-a]pyrimidine

HRID 2042192노트

반응식

HRID 2042192 반응식
Br[C:2]1[CH:3]=[N:4][C:5]2[N:6]([N:8]=[C:9]([C:11]([CH3:14])([CH3:13])[CH3:12])[N:10]=2)[CH:7]=1.[C:15]([Si:17]([CH3:20])([CH3:19])[CH3:18])#[CH:16]>>[C:11]([C:9]1[N:10]=[C:5]2[N:4]=[CH:3][C:2]([C:16]#[C:15][Si:17]([CH3:20])([CH3:19])[CH3:18])=[CH:7][N:6]2[N:8]=1)([CH3:14])([CH3:13])[CH3:12]

참가 물질

3

반응물 2

HCID 66111TrimethylsilylacetyleneHCID 583167046-Bromo-2-tert-butyl-[1,2,4]triazolo[1,5-a]pyrimidine

생성물 1

HCID 583166982-tert-Butyl-6-trimethylsilanylethynyl-[1,2,4]triazolo[1,5-a]pyrimidine

실험 절차

The title compound, a light yellow solid, MS: m/e=273.3 (M+H+), can be prepared in accordance with the general method of example 1 from 6-bromo-2-tert-butyl-[1,2,4]triazolo[1,5-a]pyrimidine (example 42, step 1) and ethynyl-trimethyl-silane.

출처 및 근거

ORD 기록
ord-87af251ddb06402e99b34cb52eb60c27
출처 데이터셋
uspto-grants-2013_11
특허 번호
US08586581B2

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