참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 1-Propanol | HCID 1031 | — |
| 반응물 | Glycine Hydrochloride | HCID 22316 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 생성물 | Propyl aminoacetate hydrochloride | HCID 2759254 | 98% |
반응 단계
To a solution of glycine hydrochloride 46 (4.5 g, 40.3 mmol) in n-propanol (60 mL) was slowly added SOCl2 (13.5 mL) at room temperature. The reaction mixture was stirred at 70° C. for 15 h. After cooling to room temperature, the mixture was evaporated under vacuum to provide the titled compound (6.1 g, 98%) as a white solid. MH+118.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08586550B2 |
|---|
| 출처 데이터셋 | uspto-grants-2013_11 |
|---|
| ORD ID | ord-edb413826c8e483ab110e8546745ee8e |
|---|
| 출처 메모 | uspto-grants-2013_11 |
|---|
