Hydrogen Bromide → HCID 20058556, 화합물

HRID 2050564노트

반응식

HRID 2050564 반응식
Cl.Cl.C[O:4][C:5]1[CH:6]=[C:7]([CH2:13][CH2:14][NH:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][NH:22][CH2:23][CH2:24][C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[CH:8]=[CH:9][C:10]=1[O:11]C.[BrH:31]>>[BrH:31].[BrH:31].[C:25]1([CH2:24][CH2:23][NH:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][NH:15][CH2:14][CH2:13][C:7]2[CH:6]=[C:5]([OH:4])[C:10]([OH:11])=[CH:9][CH:8]=2)[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1

참가 물질

3

반응물 2

HCID 260Hydrogen BromideHCID 20058526N-(2-(3,4-dimethoxyphenyl)ethyl)-N'-(2-phenyl-ethyl)hexan-1,6-diamin Dihydrochlorid

생성물 1

HCID 20058556HCID 20058556, 화합물

실험 절차

A solution of the diamine product of step (b) (4.75 g) in 48% aqueous hydrobromic acid (70 ml) was heated under reflux in an atmosphere of nitrogen for 3.5 hours. The solid which formed on cooling was filtered off and crystallised from ethanol, to give the title compound as the dihydrobromide salt, (3.1 g), mp 227°-228°.

후처리

  1. temperatureunder reflux in an atmosphere of nitrogen for 3.5 hours
  2. customThe solid which formed
  3. temperatureon cooling
  4. filtrationwas filtered off
  5. customcrystallised from ethanol

출처 및 근거

ORD 기록
ord-523249e54e0a4d21bea0bbb05956a24e
출처 데이터셋
uspto-grants-1991_05
특허 번호
US05013760

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