Sodium borohydride → 2-Chloro-alpha-methyl-3-nitrobenzenemethanol

HRID 2051235노트

반응식

HRID 2051235 반응식
[Cl:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[CH:4][C:3]=1[C:11](=[O:13])[CH3:12].[BH4-].[Na+]>>[Cl:1][C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[CH:6][CH:5]=[CH:4][C:3]=1[CH:11]([CH3:12])[OH:13]

참가 물질

3

반응물 2

HCID 4311764Sodium borohydrideHCID 124638851-(2-Chloro-3-nitrophenyl)ethanone

생성물 1

HCID 157357202-Chloro-alpha-methyl-3-nitrobenzenemethanol수율 83.4%

실험 절차

According to the procedure of Example 3, 1-(2-chloro-3-nitrophenyl)ethanone (9.0 g, 44.6 mmol) is reacted with sodium borohydride (0.84 g, 22.3 mmol) to give 2-chloro-α-methyl-3-nitrobenzenemethanol (7.5 g, 83%), mp=62-64° C.

출처 및 근거

ORD 기록
ord-196ff7a0f53c4d9fa3b2fd6c61ddd9e1
출처 데이터셋
uspto-grants-1991_05
특허 번호
US05017604

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