Hydrochloric Acid → 4-Decyloxybenzyl alcohol

HRID 2052478

반응식

HRID 2052478 반응식
B.[CH2:2]([O:12][C:13]1[CH:21]=[CH:20][C:16]([C:17](O)=[O:18])=[CH:15][CH:14]=1)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11].Cl>O1CCCC1.O>[CH2:2]([O:12][C:13]1[CH:14]=[CH:15][C:16]([CH2:17][OH:18])=[CH:20][CH:21]=1)[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH3:11]

참가 물질

6

반응물 3

HCID 313Hydrochloric AcidHCID 6331BoraneHCID 1385274-(Decyloxy)benzoic acid

생성물 1

HCID 130796524-Decyloxybenzyl alcohol

시약·촉매·용매 2

HCID 962Water용매HCID 8028Tetrahydrofuran용매2회

실험 절차

To 100 ml. of 1.0 M borane in tetrahydrofuran cooled in an ice bath under nitrogen is added dropwise, 27.8 g. of p-decyloxybenzoic acid in 300 ml. of tetrahydrofuran over a period of 45 minutes. The mixture is stirred at room temperature for 6 hours and poured onto ice, diluted with water and 10 ml. of concentrated hydrochloric acid. The mixture is filtered and the solid washed with water to give white crystals. Recrystallization from ethanol gives white plates, m.p. 57.5°-59° C.

후처리

  1. additionis added dropwise
  2. additionpoured onto ice
  3. filtrationThe mixture is filtered
  4. washthe solid washed with water
  5. customto give white crystals
  6. customRecrystallization from ethanol
  7. customgives white plates, m.p. 57.5°-59° C.

출처 및 근거

ORD 기록
ord-d5ac188512f64d4ea08b45ba858c1445
출처 데이터셋
uspto-grants-1980_01
특허 번호
US04185115

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