Hydrochloric Acid → Benzeneundecanol

HRID 2052479노트

반응식

HRID 2052479 반응식
B.[C:2]1([CH:8]([CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])C(O)=O)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl.[O:22]1CCC[CH2:23]1>O>[C:2]1([CH2:8][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:23][OH:22])[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

참가 물질

6

반응물 4

HCID 313Hydrochloric AcidHCID 6331BoraneHCID 8028Tetrahydrofuran2회HCID 211154592-Phenylundecanoic acid

생성물 1

HCID 11651716Benzeneundecanol

시약·촉매·용매 1

HCID 962Water용매

실험 절차

To 200 ml. of 1M borane in tetrahydrofuran, cooled in an ice bath under nitrogen, is added dropwise over 35 minutes, a solution of 52.5 g. of phenylundecanoic acid in 150 ml. of tetrahydrofuran. The solution is allowed to stand at room temperature for 5.5 hours and poured onto ice. To the mixture is added 8 ml. of concentrated hydrochloric acid and the mixture is diluted with water to 2.2 liters. The mixture is extracted with ether (ca 500 ml.) and the extracts dried over magnesium sulfate. Concentration in vacuo gives a colorless oil.

후처리

  1. additionis added dropwise over 35 minutes
  2. additionpoured onto ice
  3. additionTo the mixture is added 8 ml
  4. extractionThe mixture is extracted with ether (ca 500 ml.)
  5. dry with materialthe extracts dried over magnesium sulfate
  6. concentrationConcentration in vacuo
  7. customgives a colorless oil

출처 및 근거

ORD 기록
ord-6e52a21f1ba94c07a1a9b9da4c7f76da
출처 데이터셋
uspto-grants-1980_01
특허 번호
US04185115

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