2,3-Diaminotoluene → HCID 10064462, 화합물

반응식

[NH2:1][C:2]1[N:9]=[CH:8][C:7]([C:10]2[CH:15]=[CH:14][C:13]([F:16])=[CH:12][CH:11]=2)=[CH:6][C:3]=1[CH:4]=O.[NH2:17][C:18]1[C:23]([NH2:24])=[CH:22][CH:21]=[CH:20][C:19]=1[CH3:25]>>[F:16][C:13]1[CH:14]=[CH:15][C:10]([C:7]2[CH:6]=[C:3]([C:4]3[NH:24][C:23]4[CH:22]=[CH:21][CH:20]=[C:19]([CH3:25])[C:18]=4[N:17]=3)[C:2]([NH2:1])=[N:9][CH:8]=2)=[CH:11][CH:12]=1

참가 물질

반응물 2

HCID 175932,3-Diaminotoluene

HCID 58668625HCID 58668625, 화합물

생성물 1

HCID 10064462HCID 10064462, 화합물

실험 절차

Using the procedure of step (b) in Example 15, utilizing 2-amino-5-(4-fluorophenyl)nicotinaldehyde and 2,3-diaminotoluene gave 5-(4-fluorophenyl)-3-(4-methyl-1H-benzimidazol-2-yl)pyridin-2-amine.

출처 및 근거

ORD 기록: ord-6a4ad8b3ccfc4ba881a0578b27955c56
출처 데이터셋: uspto-grants-2008_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07329678B2

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