Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Azacycloundecan-2-one → 2-Methoxyazacyclododec-1-ene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Azacycloundecan-2-one | HCID 70523 | — |
| 반응물 | Sodium Bicarbonate | HCID 516892 | — |
| 반응물 | Oxonium, trimethyl-, tetrafluoroborate(1-) (1:1) | HCID 2735153 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 2-Methoxyazacyclododec-1-ene | HCID 12957742 | — |
반응 단계
2-Azacycloundecanone (0.87 g) was dissolved in 20 mL methylene chloride and stirred at room temperature under nitrogen. 1.5 g Trimethyloxonium tetrafluoroborate was added and the reaction stirred overnight. The mixture was added to saturated aqueous sodium bicarbonate and extracted with methylene chloride (2×). The combined organic layers were washed with brine, dried over magnesium sulfate, and the solvent evaporated to provide crude 2-methoxyazacyclododec-1-ene.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07329683B2 |
| 출처 데이터셋 | uspto-grants-2008_02 |
| ORD ID | ord-ebd9a9e795624384900e488e399f1f20 |
| 출처 메모 | uspto-grants-2008_02 |