Methyl iodide → 6-[[5-Methoxy-1-(4-methylphenyl)-2-phenyl-1H-benzimidazol-6-yl]oxy]hexanoic acid isopropyl ester

HRID 2054664노트

반응식

[CH:1]([O:4][C:5](=[O:35])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][O:11][C:12]1[C:13]([OH:34])=[CH:14][C:15]2[N:19]=[C:18]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[N:17]([C:26]3[CH:31]=[CH:30][C:29]([CH3:32])=[CH:28][CH:27]=3)[C:16]=2[CH:33]=1)([CH3:3])[CH3:2].[CH3:36]I>>[CH:1]([O:4][C:5](=[O:35])[CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][O:11][C:12]1[C:13]([O:34][CH3:36])=[CH:14][C:15]2[N:19]=[C:18]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[N:17]([C:26]3[CH:27]=[CH:28][C:29]([CH3:32])=[CH:30][CH:31]=3)[C:16]=2[CH:33]=1)([CH3:3])[CH3:2]

참가 물질

반응물 2

HCID 6328Methyl iodide

HCID 11995863HCID 11995863, 화합물

생성물 1

HCID 119958646-[[5-Methoxy-1-(4-methylphenyl)-2-phenyl-1H-benzimidazol-6-yl]oxy]hexanoic acid isopropyl ester

실험 절차

6-[[5-Hydroxy-1-(4-methylphenyl)-2-phenyl-1H-benzimidazol-6-yl]oxy]hexanoic acid isopropyl ester was methylated with methyl iodide according to general operating instructions 8.

출처 및 근거

ORD 기록: ord-614baf92844e4e119ff5db8dcf4321aa
출처 데이터셋: uspto-grants-2008_02
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07329679B2

반응 노트

불러오는 중…