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Hydrochloric Acid → 4-[13-(4-Chlorophenyl)-12-tridecynylamino]benzoic acid

HRID 2057643
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인쇄 미리보기

반응식

HRID 2057643 반응식
ClC1C=CC(C[CH:9]([NH:21][C:22]2[CH:32]=[CH:31][C:25]([C:26]([O:28]CC)=[O:27])=[CH:24][CH:23]=2)[CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])=CC=1.[OH-].[K+].[CH2:35](O)[CH3:36].[ClH:38]>O>[Cl:38][C:11]1[CH:12]=[CH:13][C:35]([C:36]#[C:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][NH:21][C:22]2[CH:23]=[CH:24][C:25]([C:26]([OH:28])=[O:27])=[CH:31][CH:32]=2)=[CH:9][CH:10]=1
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

6

반응물 4

HCID 313Hydrochloric AcidHCID 702EthanolHCID 14797Potassium HydroxideHCID 54279737Ethyl 4-[13-(4-chlorophenyl)-12-tridecylamino]benzoate

생성물 1

HCID 203309694-[13-(4-Chlorophenyl)-12-tridecynylamino]benzoic acid

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A 4 g. sample of ethyl 4-[13-(4-chlorophenyl)-12-tridecylamino]benzoate is hydrolyzed with 1.6 g. 85% potassium hydroxide in 60 ml. 95% ethanol by refluxing the solution for 5 hours. The solution is cooled, diluted with 100 ml. water and acidified to pH 4.5 with 37% hydrochloric acid. The precipitate is collected, dried in vacuo and crystallized from acetone to yield the title compound as a white powder.

후처리

  1. temperatureThe solution is cooled
  2. additiondiluted with 100 ml
  3. customThe precipitate is collected
  4. customdried in vacuo
  5. customcrystallized from acetone

출처 및 근거

ORD 기록
ord-febc975e5be742cea81f97208dd0eb00
출처 데이터셋
uspto-grants-1980_07
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US04211783

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