Formic Acid → HCID 54372587, 화합물

HRID 2057746노트

반응식

HRID 2057746 반응식
[C:1]1([NH:7][N:8]=[CH:9][C:10]2[CH:11]=[N:12][CH:13]=[CH:14][CH:15]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:16](OC=O)(=[O:18])C.C(O)=O.C(OC(=O)C)(=O)C>C(Cl)Cl>[CH:16]([N:7]([C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)[N:8]=[CH:9][C:10]1[CH:11]=[N:12][CH:13]=[CH:14][CH:15]=1)=[O:18]

참가 물질

6

반응물 4

HCID 284Formic AcidHCID 7918Acetic AnhydrideHCID 75269Acetic-formic anhydrideHCID 2587553-Pyridinecarbaldehyde phenylhydrazone

생성물 1

HCID 54372587HCID 54372587, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

9.85 g of 3 (prepared as described in Example 3) was dissolved in 50 ml of dry methylene chloride. 15 ml of formic acetic anhydride (prepared by mixing the appropriate amounts of formic acid and acetic anhydride) was added. The mixture was allowed to stand overnight at room temperature. The solvent was evaporated under reduced pressure. The residue was dissolved in ether. The solution was washed with sodium bicarbonate solution, dried (Na2SO4) and the solvent evaporated to give 4, as a white crystalline solid, mp 129°-132° C.

후처리

  1. additionwas added
  2. customThe solvent was evaporated under reduced pressure
  3. dissolutionThe residue was dissolved in ether
  4. washThe solution was washed with sodium bicarbonate solution
  5. dry with materialdried (Na2SO4)
  6. customthe solvent evaporated
  7. customto give 4

출처 및 근거

ORD 기록
ord-d749a427e2544d50b8c4b7888d1299c3
출처 데이터셋
uspto-grants-1980_07
특허 번호
US04212868

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