Imidazole → 1-Cyclooctylmethylimidazole

HRID 2058442노트

반응식

HRID 2058442 반응식
[NH:1]1[CH:5]=[CH:4][N:3]=[CH:2]1.[Na].Br[CH2:8][CH:9]1[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1>C(O)C>[CH:9]1([CH2:8][N:1]2[CH:5]=[CH:4][N:3]=[CH:2]2)[CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1

참가 물질

5

반응물 3

HCID 795ImidazoleHCID 5360545SodiumHCID 18459730(Bromomethyl)cyclooctane

생성물 1

HCID 205502381-Cyclooctylmethylimidazole

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

Imidazole (2.0 g, 0.03 mol) was added to a solution of sodium (0.7 g, 0.03 mol) in dry ethanol (50 ml). The mixture was stirred and heated to boiling when bromomethylcyclooctane (5.5 g, 0.027 mol) was added dropwise. Following the addition, the reaction mixture was stirred and boiled for 15 h.

후처리

  1. temperatureheated
  2. additionwas added dropwise
  3. additionthe addition
  4. stirringthe reaction mixture was stirred

출처 및 근거

ORD 기록
ord-17299225e1134e1b85d1cdd3e88ce6e3
출처 데이터셋
uspto-grants-1982_03
특허 번호
US04317830

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