Chloroacetyl chloride → HCID 13021162, 화합물

HRID 2058940

반응식

HRID 2058940 반응식
[CH3:1][C:2]1([CH3:9])[CH2:6][CH:5]([CH3:7])[CH2:4][C:3]1=O.CC1CC(C)(C)CC1=O.S([O-])([O-])(=O)=O.[NH4+].[NH4+].C(N)C=C.ClCC(Cl)=O.C(N(CC)CC)C.C[C:43]1(C)CC(C)[C:45]([N:49](CC=C)[C:50](=[O:53])[CH2:51][Cl:52])=[CH:44]1.CC1CC(C)(C)C(N(CC=C)C(=O)CCl)=C1>C1C=CC=CC=1>[CH3:7][C:5]1[CH2:6][C:2]([CH3:9])([CH3:1])[CH2:3][C:4]=1[N:49]([CH2:45][CH:44]=[CH2:43])[C:50](=[O:53])[CH2:51][Cl:52]

참가 물질

10

반응물 8

HCID 6577Chloroacetyl chlorideHCID 7853AllylamineHCID 8471TriethylamineHCID 1073242,4,4-TrimethylcyclopentanoneHCID 1196322,2,4-TrimethylcyclopentanoneHCID 6097028Ammonium SulfateHCID 13021160HCID 13021160, 화합물HCID 13021161HCID 13021161, 화합물

생성물 1

HCID 13021162HCID 13021162, 화합물

시약·촉매·용매 1

HCID 241Benzene용매3회

실험 절차

By the same procedure as in Example 63 using a mixture comprising 2,2,4-trimethylcyclopentanone and 2,4,4-trimethylcyclopentanone (about 1:1) (25.2 parts by weight; 0.2 mole) in 0.2 liter of benzene, 0.1 part by weight of ammonium sulfate, and 11.4 parts by weight (0.2 mole) of allylamine, further reacted with 22.6 parts by weight (0.2 mole) of chloracetyl chloride in 0.05 liter of benzene and 22 parts by weight (0.2 mole) of triethylamine in 0.1 liter of benzene, a mixture of isomers consisting of N-(3,3,5-trimethylcyclopenten-1-yl)-N-allyl-α-chloroacetamide, N-(3,5,5-trimethylcyclopenten-1-yl)-N-allyl-α-chloroacetamide, and N-(2,4,4-trimethylcyclopenten-1-yl)-N-allyl-α-chloroacetamide was obtained. The yield of brown oily distillate (B.P.=88°-93° C. at 1.0 torr) having a refractive index (nD20 =1.4978) was 29 parts by weight. The content of organically combined chlorine was 15.9% (14.7%). The nitrogen content was 6.1% (5.8%).

후처리

  1. additiona mixture of isomers

출처 및 근거

ORD 기록
ord-dca8fee64b6548ecab7c62a651f09001
출처 데이터셋
uspto-grants-1982_03
특허 번호
US04319918

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