2,6-Dichlorobenzoyl chloride → 2,6-Dichloro-N-(3-benzisoxazolyl)benzamide

HRID 2059235

반응식

HRID 2059235 반응식
[NH2:1][C:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[O:4][N:3]=1.[Cl:11][C:12]1[CH:20]=[CH:19][CH:18]=[C:17]([Cl:21])[C:13]=1[C:14](Cl)=[O:15]>C1(C)C=CC=CC=1>[Cl:11][C:12]1[CH:20]=[CH:19][CH:18]=[C:17]([Cl:21])[C:13]=1[C:14]([NH:1][C:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[O:4][N:3]=1)=[O:15]

참가 물질

4

반응물 2

HCID 783922,6-Dichlorobenzoyl chlorideHCID 27797491,2-Benzoxazol-3-amine

생성물 1

HCID 205467542,6-Dichloro-N-(3-benzisoxazolyl)benzamide

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

3-Aminobenzisoxazole (2 gram), 2,6-dichlorobenzoylchloride (2 gram), and 50 ml. of toluene are heated at reflux for 16 hours. After evaporation of the solvent at reduced pressure, the resultant oily semi-solid is triturated with ether. The solid so formed is then washed with ether and water and constitutes the desired product.

후처리

  1. temperatureat reflux for 16 hours
  2. customAfter evaporation of the solvent at reduced pressure
  3. customthe resultant oily semi-solid is triturated with ether
  4. customThe solid so formed
  5. washis then washed with ether and water

출처 및 근거

ORD 기록
ord-4944d88c8d17409192df679111a9782c
출처 데이터셋
uspto-grants-1982_03
특허 번호
US04322429

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