Methyl p-toluenesulfonate → Pyridinium, 4-acetyl-1-methyl-, 4-methylbenzenesulfonate (1:1)

HRID 2059497노트

반응식

HRID 2059497 반응식
[C:1]([C:4]1[CH:9]=[CH:8][N:7]=[CH:6][CH:5]=1)(=[O:3])[CH3:2].[CH3:10][O:11][S:12]([C:15]1[CH:20]=[CH:19][C:18]([CH3:21])=[CH:17][CH:16]=1)(=[O:14])=[O:13]>C(O)C>[C:18]1([CH3:21])[CH:17]=[CH:16][C:15]([S:12]([O-:14])(=[O:11])=[O:13])=[CH:20][CH:19]=1.[C:1]([C:4]1[CH:9]=[CH:8][N+:7]([CH3:10])=[CH:6][CH:5]=1)(=[O:3])[CH3:2]

참가 물질

4

반응물 2

HCID 6645Methyl p-toluenesulfonateHCID 142824-Acetylpyridine

생성물 1

HCID 53250141Pyridinium, 4-acetyl-1-methyl-, 4-methylbenzenesulfonate (1:1)

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

4-Acetylpyridine (30.0 g, 0.25 mol) and p-toluene sulfonic acid methyl ester (55.8 g, 0.30 mol) in 500 ml ethanol were heated under reflux for 5 hours. The solvent was removed under vacuum in a rotary evaporator and the residue was taken up in ether. After separating off the ether phase, the product slowly crystallized out. The product was dried under vacuum.

후처리

  1. temperatureunder reflux for 5 hours
  2. customThe solvent was removed under vacuum in a rotary evaporator
  3. customAfter separating off the ether phase
  4. customthe product slowly crystallized out
  5. customThe product was dried under vacuum

출처 및 근거

ORD 기록
ord-8b3bc44f5cf34c75830b17b4c56ae364
출처 데이터셋
uspto-grants-2012_10
특허 번호
US08277517B2

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