Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 2-(Piperidin-1-yl)acetic acid hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Water | HCID 962 | — |
| 반응물 | 1-Piperidineacetic acid, ethyl ester | HCID 643466 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | 2-(Piperidin-1-yl)acetic acid hydrochloride | HCID 201096 | 83% |
반응 단계
Ethyl 2-(piperidin-1-yl)-acetate (5.5 g, 32.2 mmol), water (12 ml) and c HCl (3 ml) were heated under reflux for 20 hours. Volatile components were evaporated under reduced pressure to leave an off white solid. This solid was co-evaporated with toluene (50 ml×3) and dried in vacuo to give an off white powder (Yield 4.8 g, 83%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08278448B2 |
| 출처 데이터셋 | uspto-grants-2012_10 |
| ORD ID | ord-d3dc8b9fea3b481caa28aea72c20a86a |
| 출처 메모 | uspto-grants-2012_10 |