Dehydroepiandrosterone → Dehydroepiandrosterone

HRID 2062045

반응식

HRID 2062045 반응식
[CH3:1][C@@:2]12[C:10](=[O:11])[CH2:9][CH2:8][C@H:7]1[C@@H:6]1[CH2:12][CH:13]=[C:14]3[CH2:19][C@@H:18]([OH:20])[CH2:17][CH2:16][C@:15]3([CH3:21])[C@H:5]1[CH2:4][CH2:3]2.[CH3:22][C@@:23]12[C:31](=[O:32])[CH2:30][CH2:29][C@H:28]1[C@@H:27]1[CH2:33][CH:34]=[C:35]3[CH2:40][C@@H:39]([O:41]S(O)(=O)=O)[CH2:38][CH2:37][C@:36]3([CH3:46])[C@H:26]1[CH2:25][CH2:24]2>>[CH3:1][C@@:2]12[C:10](=[O:11])[CH2:9][CH2:8][C@H:7]1[C@@H:6]1[CH2:12][CH:13]=[C:14]3[CH2:19][C@@H:18]([OH:20])[CH2:17][CH2:16][C@:15]3([CH3:21])[C@H:5]1[CH2:4][CH2:3]2.[CH3:22][C@@:23]12[C@@H:31]([OH:32])[CH2:30][CH2:29][C@H:28]1[C@@H:27]1[CH2:33][CH2:34][C:35]3[C@@:36]([CH3:46])([C@H:26]1[CH2:25][CH2:24]2)[CH2:37][CH2:38][C:39](=[O:41])[CH:40]=3

참가 물질

4

반응물 2

HCID 5881DehydroepiandrosteroneHCID 12594Dehydroepiandrosterone Sulfate

생성물 2

HCID 5881DehydroepiandrosteroneHCID 6013Testosterone

실험 절차

Dehydroepiandrosterone (DHEA) [(3β-hydroxy-5-androsten-17-one)] is a weak androgen synthesized by the adrenal cortex. It has a short plasma half-life and is usually converted to dehydroepiandrosterone sulfate (DHEA-S). Excessive DHEA secretion can produce acne, hirsutism and virilization via conversion to testosterone.

후처리

  1. customsynthesized by the adrenal cortex

출처 및 근거

ORD 기록
ord-603f73e040f64415991d5e84a8bbb485
출처 데이터셋
uspto-grants-2012_10
특허 번호
US08283627B2

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