Dichloromethane → 1-[2-(4-bromomethyl-phenyl)ethyl]-4-(2-fluoro-benzyloxy)-1H-pyridin-2-one

반응식

[Cl:31][CH2:32][Cl:33].[F:1][c:2]1[c:3]([CH2:4][O:5][c:6]2[cH:7][c:8](=[O:22])[n:9]([CH2:12][CH2:13][c:14]3[cH:15][cH:16][c:17]([CH2:20][OH:21])[cH:18][cH:19]3)[cH:10][cH:11]2)[cH:23][cH:24][cH:25][cH:26]1.[P:27]([Br:28])([Br:29])[Br:30]>>[F:1][c:2]1[c:3]([CH2:4][O:5][c:6]2[cH:7][c:8](=[O:22])[n:9]([CH2:12][CH2:13][c:14]3[cH:15][cH:16][c:17]([CH2:20][Br:28])[cH:18][cH:19]3)[cH:10][cH:11]2)[cH:23][cH:24][cH:25][cH:26]1

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 24614Phosphorus tribromide

HCID 670072854-(2-Fluoro-benzyloxy)-1-[2-(4-hydroxymethyl-phenyl)-ethyl]-1H-pyridin-2-one

생성물 1

HCID 670066651-[2-(4-bromomethyl-phenyl)ethyl]-4-(2-fluoro-benzyloxy)-1H-pyridin-2-one

출처 및 근거

ORD 기록: ord-0d885d77e00c40478f6e75a26c1330ce
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

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