Butanal → Benzyl-((E)-but-1-enyl)-amine

HRID 2066883노트

반응식

HRID 2066883 반응식
[CH2:1]([NH2:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:9](=O)[CH2:10][CH2:11][CH3:12].[OH-].[K+]>>[CH2:1]([NH:8]/[CH:9]=[CH:10]/[CH2:11][CH3:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

4

반응물 3

HCID 261ButanalHCID 7504BenzylamineHCID 14797Potassium Hydroxide

생성물 1

HCID 15360338Benzyl-((E)-but-1-enyl)-amine수율 74.4%

실험 절차

To benzylamine (5.46 mL, 50 mmol), at 0° C., was added butyraldehyde (4.51 mL, 50 mmol). The mixture was warmed to room temperature and KOH (1.5 g) was added. The mix was stirred at room temperature for 15 minutes, the water was removed and 0.5 g of KOH was added. The mixture was stirred at room temperature overnight and filtered to remove the KOH to yield 6 g (74%) of 62a.

후처리

  1. customthe water was removed
  2. addition0.5 g of KOH was added
  3. stirringThe mixture was stirred at room temperature overnight
  4. filtrationfiltered
  5. customto remove the KOH

출처 및 근거

ORD 기록
ord-98abbb7e88b24a96beaa2127597d52bf
출처 데이터셋
uspto-grants-2012_10
특허 번호
US08293729B2

반응 노트

불러오는 중…