Acetic Anhydride → N-Benzyl-N-((E)-but-1-enyl)-acetamide

HRID 2066884노트

반응식

HRID 2066884 반응식
[CH2:1]([NH:8]/[CH:9]=[CH:10]/[CH2:11][CH3:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(N(CC)CC)C.[C:20](OC(=O)C)(=[O:22])[CH3:21]>C1(C)C=CC=CC=1>[CH2:1]([N:8](/[CH:9]=[CH:10]/[CH2:11][CH3:12])[C:20](=[O:22])[CH3:21])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

5

반응물 3

HCID 7918Acetic AnhydrideHCID 8471TriethylamineHCID 15360338Benzyl-((E)-but-1-enyl)-amine

생성물 1

HCID 13494620N-Benzyl-N-((E)-but-1-enyl)-acetamide

시약·촉매·용매 1

HCID 1140Toluene용매

반응 조건

온도
0 °C

실험 절차

To 62a (3.22 g, 20 mmol) in 10 mL of toluene, was added triethylamine (2.79 mL, 20 mmol). The mixture was cooled to 0° C. and acetic anhydride (1.89 mL, 20 mmol) was added dropwise. The mixture was warmed to room temperature and stirred overnight. It was then concentrated on high vacuum to give crude 62b.

후처리

  1. temperatureThe mixture was warmed to room temperature
  2. concentrationIt was then concentrated on high vacuum

출처 및 근거

ORD 기록
ord-cd85b76f62644e16b5d6b84171cc7b09
출처 데이터셋
uspto-grants-2012_10
특허 번호
US08293729B2

반응 노트

불러오는 중…