HCID 85848304, 화합물 → HCID 85848305, 화합물
반응식
[CH2:1]([N:3]1[CH2:10][CH:9]2[CH:5]([CH2:6][CH2:7][CH2:8]2)[C:4]1=[CH:11][N+:12]([O-])=O)[CH3:2]>[Ni].CO>[CH2:1]([N:3]1[CH2:10][CH:9]2[CH:5]([CH2:6][CH2:7][CH2:8]2)[CH:4]1[CH2:11][NH2:12])[CH3:2]참가 물질
4
실험 절차
54 parts of N-ethyl-2-nitromethylene-3-azabicyclo (3,3,0) octane, in solution in 500 parts of anhydrous methanol were reduced in presence of 20 parts of Raney Nickel at 5 kg/m2 pressure. After filtration and washing of the catalyst by methanol, the filtrate was evaporated under vacuo then distilled. There were obtained 30 parts of N-ethyl-2-aminomethyl-3-azabicyclo (3,3,0) octane, B.P./0.25-0,30 mm Hg : 88°-90° C. This reduction can be easily carried out with lithium aluminium hydride too.
후처리
- filtrationAfter filtration
- washwashing of the catalyst by methanol
- customthe filtrate was evaporated under vacuo
- distillationthen distilled
출처 및 근거
- ORD 기록
- ord-3ac39c3b0fe74d518d9f8673d7e53ab8
- 출처 데이터셋
- uspto-grants-1977_09
- 특허 번호
- US04048321
반응 노트
불러오는 중…