Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Tetrafluoro-m-phenylenediamine dihydrochloride → 3-(2-Imidazolyl)propylguanidine sulphate monohydrate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Tetrafluoro-m-phenylenediamine dihydrochloride | HCID 149026 | — |
| 반응물 | S-methyl isothiourea hemisulfate | HCID 6604939 | — |
| 반응물 | 3-(1H-Imidazol-2-yl)propan-1-amine | HCID 13290797 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 3-(2-Imidazolyl)propylguanidine sulphate monohydrate | HCID 178512791 | — |
반응 단계
A solution of 2-(3-aminopropyl)imidazole, prepared from its dihydrochloride (0.9 g) by means of an ion-exchange resin (OH-1), and S-methylthiouronium sulphate (1.26 g) in water (20 ml) is heated under reflux for 18 hours. The product, isolated in a manner similar to that described in Example 1, is recrystallized from aqueous ethanol yielding 3-(2-imidazolyl)propylguanidine sulphate monohydrate, m.p. 260°-262° C. (dec.).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04048319 |
| 출처 데이터셋 | uspto-grants-1977_09 |
| ORD ID | ord-28aaf3c386ee4e8f96d9b794fe3019b8 |
| 출처 메모 | uspto-grants-1977_09 |