Benzene → 3-methyl-4-(trichloroacetamido)phenyl N-methylcarbamate
반응식
[CH3:1][NH:2][C:3](=[O:13])[O:4][C:5]1[CH:10]=[CH:9][C:8]([NH2:11])=[C:7]([CH3:12])[CH:6]=1.C(N(CC)CC)C.C1C=CC=CC=1.[Cl:27][C:28]([Cl:33])([Cl:32])[C:29](Cl)=[O:30]>O>[CH3:1][NH:2][C:3](=[O:13])[O:4][C:5]1[CH:10]=[CH:9][C:8]([NH:11][C:29](=[O:30])[C:28]([Cl:33])([Cl:32])[Cl:27])=[C:7]([CH3:12])[CH:6]=1참가 물질
6
실험 절차
To a slurry of 3-methyl-4-aminophenyl N-methylcarbamate (1.8g., 0.01 mole), triethylamine (1.11g., 0.011 mole), and 25 ml. of benzene was added trichloroacetyl chloride (2.0g., 0.011 mole) dropwise. After refluxing for one hour, the reaction mixture was poured into water and the resulting solid product was filtered (3.05g., m.p. 185°-87° C.).
후처리
- temperatureAfter refluxing for one hour
- filtrationthe resulting solid product was filtered (3.05g., m.p. 185°-87° C.)
출처 및 근거
- ORD 기록
- ord-a7cd5996b78b4f96bd4479f3e7a24945
- 출처 데이터셋
- uspto-grants-1977_09
- 특허 번호
- US04051254
반응 노트
불러오는 중…