5-(Methylthio)-8-(3-(trifluoromethyl)phenyl)-3H,6H-1,4,5a,8a-tetraazaacenaphthylen-3-one → 5-[(Phenylmethyl)amino)-8-[3-(trifluoromethyl)phenyl]-3H,6H-1,4,5a,8a-tetraazaacenaphthylen-3-one

HRID 2073197

반응식

HRID 2073197 반응식
CS[C:3]1[N:13]2[C:14]3[N:9]([C:10]([C:15]4[CH:20]=[CH:19][CH:18]=[C:17]([C:21]([F:24])([F:23])[F:22])[CH:16]=4)=[CH:11][CH2:12]2)[N:8]=[CH:7][C:6]=3[C:5](=[O:25])[N:4]=1>C(N)C1C=CC=CC=1>[C:15]1([CH2:10][NH:9][C:3]2[N:13]3[C:14]4[N:9]([C:10]([C:15]5[CH:20]=[CH:19][CH:18]=[C:17]([C:21]([F:22])([F:23])[F:24])[CH:16]=5)=[CH:11][CH2:12]3)[N:8]=[CH:7][C:6]=4[C:5](=[O:25])[N:4]=2)[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

참가 물질

3

반응물 1

HCID 98853995-(Methylthio)-8-(3-(trifluoromethyl)phenyl)-3H,6H-1,4,5a,8a-tetraazaacenaphthylen-3-one

생성물 1

HCID 212239495-[(Phenylmethyl)amino)-8-[3-(trifluoromethyl)phenyl]-3H,6H-1,4,5a,8a-tetraazaacenaphthylen-3-one

시약·촉매·용매 1

HCID 7504Benzylamine용매

실험 절차

A 200 mg amount of 5-(methylthio)-8-[3-trifluoromethyl)phenyl]-3H,6H-1,4,5a,8a-tetraazaacenaphthylen-3-one (prepared as described in Example 9) was suspended in 10.0 ml of benzylamine. The reaction mixture was cooled to room temperature and filtered. The solid on the filter was washed with ether and air dried to give 189 mg of the product of the example as a white solid, m.p. 220°-224° C.

후처리

  1. filtrationfiltered
  2. washThe solid on the filter was washed with ether and air
  3. customdried

출처 및 근거

ORD 기록
ord-33e2e1aa970946798fd05a4c0061b597
출처 데이터셋
uspto-grants-1990_04
특허 번호
US04916137

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