4-Chloro-3-nitrobenzenesulfonamide → 4-hydrazinyl-3-nitrobenzene-1-sulfonamide

HRID 2073240노트

반응식

HRID 2073240 반응식
O.[NH2:2][NH2:3].Cl[C:5]1[CH:10]=[CH:9][C:8]([S:11]([NH2:14])(=[O:13])=[O:12])=[CH:7][C:6]=1[N+:15]([O-:17])=[O:16]>C(O)C>[N+:15]([C:6]1[CH:7]=[C:8]([S:11](=[O:13])(=[O:12])[NH2:14])[CH:9]=[CH:10][C:5]=1[NH:2][NH2:3])([O-:17])=[O:16]

참가 물질

4

반응물 2

HCID 73244-Chloro-3-nitrobenzenesulfonamideHCID 24654Hydrazine hydrate (1:1)

생성물 1

HCID 32513014-hydrazinyl-3-nitrobenzene-1-sulfonamide수율 93.4%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

20 ml of hydrazine hydrate were added to a suspension of 47.33 g of 4-chloro-3-nitrobenzenesulfonamide [prepared as described in: J. Am. Chem. Soc. 73, 2558 (1951)] in 200 ml of abs. ethanol. The mixture was boiled under stirring for 30 minutes, then cooled down. The crystals were filtered by suction and thoroughly washed with water to obtain 43.38 g (93.4%) of 2-nitro-4-sulfamoylphenylhydrazine, m.p.: 217°-218° C. (with decomposition).

후처리

  1. temperaturecooled down
  2. filtrationThe crystals were filtered by suction
  3. washthoroughly washed with water

출처 및 근거

ORD 기록
ord-50a040bc31c94b1882c25be56ec047d6
출처 데이터셋
uspto-grants-1990_04
특허 번호
US04916149

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