Benzoyl Peroxide → HCID 19858052, 화합물

HRID 2073388노트

반응식

HRID 2073388 반응식
[CH3:1][C:2]1([CH3:19])[C:6](=[O:7])[O:5][C:4]2[CH:8]=[CH:9][C:10]3[C:15]([C:3]1=2)=[CH:14][C:13]([CH3:16])=[C:12]([C:17]#[N:18])[CH:11]=3.[Br:20]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[Br:20][CH2:16][C:13]1[CH:14]=[C:15]2[C:10]([CH:9]=[CH:8][C:4]3[O:5][C:6](=[O:7])[C:2]([CH3:19])([CH3:1])[C:3]=32)=[CH:11][C:12]=1[C:17]#[N:18]

참가 물질

5

반응물 3

HCID 7187Benzoyl PeroxideHCID 67184N-bromobutanimideHCID 19858070HCID 19858070, 화합물

생성물 1

HCID 19858052HCID 19858052, 화합물

시약·촉매·용매 1

HCID 5943Carbon Tetrachloride용매

실험 절차

A mixture of 1,2-dihydro-1,1,8-trimethyl-2-oxonaphtho[2,1-b]furan-7-carbonitrile, (0.25 g), N-bromosuccinimide (0.2 g), benzoyl peroxide (0.01 g) and carbon tetrachloride (40 ml) was stirred under reflux for 24 h. The reaction mixture was cooled, washed with water, dried and evaporated to dryness under reduced pressure, to give the required starting material, 8-bromomethyl-1,2-dihydro-1,1-dimethyl-2-oxonaphtho[2,1-b]furan-7-carbonitrile, which was used without further purification.

후처리

  1. temperatureunder reflux for 24 h
  2. temperatureThe reaction mixture was cooled
  3. washwashed with water
  4. customdried
  5. customevaporated to dryness under reduced pressure

출처 및 근거

ORD 기록
ord-d6e88b7ab9ea4d279e7cdea699f3ef18
출처 데이터셋
uspto-grants-1990_04
특허 번호
US04916148

반응 노트

불러오는 중…